TY - JOUR T1 - Amfifil polimer kotérhálók: egy újszerű nanoszerkezetű anyagcsoport JF - Magyar Kémiai Folyóirat - Kémiai Közlemények Y1 - 2015 A1 - Szabó, Ákos A1 - Mezey, Péter A1 - Fodor, Csaba A1 - Domján, Attila A1 - Kali, Gergely A1 - Stumphauser, Tímea A1 - Erdődi, Gábor A1 - Thomann, Ralf A1 - Németh, Péter A1 - Szanka, István A1 - Illés, Gergely A1 - Haraszti, Márton A1 - Pásztor, Szabolcs A1 - Bóta, Attila A1 - András Wacha A1 - Süvegh, Károly A1 - Iván, Béla KW - no-peer-review VL - 121 ER - TY - JOUR T1 - Vanadium dispersion and catalytic activity of Pd/VOx/SBA-15 catalysts in the Wacker oxidation of ethylene JF - Microporous and Mesoporous Materials Y1 - 2015 A1 - Barthos, Róbert A1 - Hegyessy, András A1 - Klébert, Szilvia A1 - Valyon, József KW - H2-TPR KW - Pd/V catalysts KW - SBA-15 KW - UV–Vis KW - Wacker oxidation AB - Transmission electron microscopy (TEM), X-ray diffractometry (XRD), in situ diffuse reflectance ultra violet – visible (UV–Vis) spectroscopy, and temperature-programmed reduction by hydrogen (H2-TPR) were used to identify the vanadia forms in vanadium-containing SBA-15 preparations (VOx/SBA-15). Wacker type supported Pd/VOx/SBA-15 catalysts were obtained by introducing Pd into VOx/SBA-15 samples using conventional impregnation method. The activity of the catalysts was tested in the gas phase partial oxidation of ethylene by O2 in the presence of H2O (Wacker oxidation). VOx/SBA-15 sample was obtained by micelle-templated synthesis using vanadium-containing synthesis gel. The vanadium became incorporated in the silica structure from the gel in near to atomic dispersion. This catalyst was quite active in ethylene oxidation to CO2 but had low Wacker activity. Isolated, polymeric and bulk vanadia species were identified in the VOx/SBA-15 prepared by wet impregnation/calcination method. The specific surface area of the sample was found to be smaller than that of the neat SBA-15 support because some pores were blocked by vanadia agglomerates. The corresponding Pd/VOx/SBA-15 catalyst showed high selectivity for acetaldehyde formation but the activity was relatively low due to low accessible active surface. A third VOx/SBA-15 sample was obtained by applying directed surface reaction between silanol groups of dehydrated SBA-15 and anhydrous solution of vanadyl acetylacetonate. Large number of accessible Pd/VOx sites were present in the corresponding Pd/VOx/SBA-15 catalyst. Latter catalyst induced ethylene oxidation to acetaldehyde with high yield at temperatures ≤160 °C and with good yield to acetic acid at temperatures ≥160 °C. VL - 207 SN - 1387-1811 UR - http://www.sciencedirect.com/science/article/pii/S1387181115000050 JO - Microporous and Mesoporous Materials ER - TY - JOUR T1 - Mechanical Stability and Fibrinolytic Resistance of Clots Containing Fibrin, DNA, and Histones JF - Journal of Biological ChemistryJournal of Biological Chemistry Y1 - 2013 A1 - Longstaff, Colin A1 - Varjú, Imre A1 - Sótonyi, Péter A1 - Szabó, László A1 - Krumrey, Michael A1 - Hoell, Armin A1 - Bóta, Attila A1 - Varga, Zoltán A1 - Komorowicz, Erzsébet A1 - Kolev, Krasimir KW - DNA KW - Fibrinolysis KW - Histones KW - Neutrophil KW - Neutrophil Extracellular Trap KW - Tissue Plasminogen Activator (tPA) AB -

Neutrophil extracellular traps are networks of DNA and associated proteins produced by nucleosome release from activated neutrophils in response to infection stimuli and have recently been identified as key mediators between innate immunity, inflammation, and hemostasis. The interaction of DNA and histones with a number of hemostatic factors has been shown to promote clotting and is associated with increased thrombosis, but little is known about the effects of DNA and histones on the regulation of fibrin stability and fibrinolysis. Here we demonstrate that the addition of histone-DNA complexes to fibrin results in thicker fibers (increase in median diameter from 84 to 123 nm according to scanning electron microscopy data) accompanied by improved stability and rigidity (the critical shear stress causing loss of fibrin viscosity increases from 150 to 376 Pa whereas the storage modulus of the gel increases from 62 to 82 pascals according to oscillation rheometric data). The effects of DNA and histones alone are subtle and suggest that histones affect clot structure whereas DNA changes the way clots are lysed. The combination of histones + DNA significantly prolongs clot lysis. Isothermal titration and confocal microscopy studies suggest that histones and DNA bind large fibrin degradation products with 191 and 136 nm dissociation constants, respectively, interactions that inhibit clot lysis. Heparin, which is known to interfere with the formation of neutrophil extracellular traps, appears to prolong lysis time at a concentration favoring ternary histone-DNA-heparin complex formation, and DNase effectively promotes clot lysis in combination with tissue plasminogen activator.

VL - 288 SN - 0021-9258, 1083-351X UR - http://www.jbc.org/content/288/10/6946 IS - 10 JO - J. Biol. Chem. ER - TY - ICOMM T1 - Probing Nanoscale Structures - The SANS Toolbox Y1 - 2012 A1 - Hammouda, Boualem JF - Probing Nanoscale Structures - The SANS ToolboxProbing Nanoscale Structures - The SANS Toolbox UR - http://www.ncnr.nist.gov/staff/hammouda/the_SANS_toolbox.pdf ER - TY - JOUR T1 - Small-angle X-ray scattering experiments and computer simulations to characterise anisotropy of activated carbons prepared from wood JF - CarbonCarbon Y1 - 2011 A1 - András Wacha A1 - Varga, Zoltán A1 - Vainio, Ulla A1 - Hoell, Armin A1 - Bóta, Attila VL - 49 SN - 00086223 UR - http://linkinghub.elsevier.com/retrieve/pii/S0008622311003988 IS - 12 ER - TY - JOUR T1 - A Closer Look at the Structure of Sterically Stabilized Liposomes: A Small-Angle X-ray Scattering Study JF - The Journal of Physical Chemistry BThe Journal of Physical Chemistry B Y1 - 2010 A1 - Varga, Zoltán A1 - Berényi, Szilvia A1 - Szokol, Bálint A1 - Őrfi, László A1 - Kéri, György A1 - Peták, István A1 - Hoell, Armin A1 - Bóta, Attila VL - 114 SN - 1520-6106, 1520-5207 UR - http://pubs.acs.org/doi/abs/10.1021/jp9109207 IS - 20 JO - A Closer Look at the Structure of Sterically Stabilized Liposomes ER - TY - BOOK T1 - X-ray Data Booklet Y1 - 2009 A1 - Attwood, David A1 - Gullikson, Eric A1 - Howells, Malcolm A1 - Kim, Kwang-Je A1 - Kirz, Janos A1 - Kortright, Jeffrey A1 - Lindau, Ingolf A1 - Liu, Yanwei A1 - Pianetta, Piero A1 - Robinson, Arthur A1 - Scofield, James A1 - Underwood, James A1 - Williams, Gwyn A1 - Winick, Herman PB - Lawrence Berkeley National Laboratory, University of California CY - Berkeley, CA UR - http://xdb.lbl.gov ER -